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July 4th
- Dopamine D1 and D5 Receptors Are Localized to Discrete Populations of Interneurons in Primate Prefrontal Cortex -- Glausier et al. 19 (8): 1820 -- Cerebral Cortex: D1 was the predominant D1R subtype in PV interneurons and was found mainly in dendrites. In contrast, D5 was the predominant D1R subtype in CR interneurons and was found mainly in dendrites.
July 2nd
- Ligand-Gated Chloride Channels Are Receptors for Biogenic Amines in C. elegans -- Ringstad et al. 325 (5936): 96 -- Science: LGC-53 is a high-affinity dopamine receptor, LGC-55 is a high-affinity tyramine receptor, and LGC-40 is a low-affinity serotonin receptor that is also gated by choline and acetylcholine. All are ligand-gated chloride channels.
- DECONSTRUCTING THE VANILLA MILKSHAKE: THE DOMINANT EFFECT OF SUCROSE ON SELF-ADMINISTR ATION OF NUTRIENT-FLAVO R MIXTURES
July 1st
- Dopamine Transporters in Striatum may contribute to modulation of Attention
- New, Unmedicated Parkies Have Trouble Learning From Rewards: So, if you have early Parkinson?s disease, you?re not taking meds for it yet, and your wife says you?ll get some extra lovin? if you do the dishes tonight? a newly-released test reveals the new Parkie might not LEARN that ?taking out garbage? equals ?extra lovin??.
June 29th
- Mind Hacks: The straight dopamine theory could be up in smoke
- Ventral Tegmental Area BDNF Induces an Opiate-Depende nt-Like Reward State in Naive Rats -- Vargas-Perez et al. 324 (5935): 1732 -- Science: A single infusion of BDNF into the VTA promotes a shift from a dopamine-indep endent to a dopamine-depen dent opiate reward system, identical to that seen when an opiate-naïve rat becomes dependent and withdrawn. This shift involves a switch in the {gamma}-aminob utyric acid type A (GABAA) receptors of VTA GABAergic neurons, from inhibitory to excitatory signaling.
- Dopaminergic transplantatio n for parkinson's disease: Current status and future prospects: "Collecti vely, these findings do not bode well for the short-term future of cell-based dopaminergic therapies in Parkinson' ;s disease."
June 27th
- Low Dopamine Levels ==> How to Increase?: Got the remainder of my most recent blood test results. Dopamine level is really, really low. I don't have the paperwork in front of me, but my
- The brain-addictio n connection : Crystal meth (speed), and our good friend dopamine: The brain-drugs relationship can sometimes be complex, but this article tries to simplify things for readers so that they have a basic understanding of what happens when certain drugs are used. This one deals with crystal meth (speed) and the way it affects dopamine in the brain.
June 25th
- New depression drug wins Mich. development funding | detnews.com | The Detroit News: Michigan Technology and Research Institute
June 22nd
- ScienceDirect - Cognitive Brain Research : Increased dopamine tone during meditation-ind uced change of consciousness: ll participants reported a decreased desire for action during meditation, along with heightened sensory imagery. The level of gratification and the depth of relaxation did not differ between the attention and meditation conditions. Here we show increased striatal dopamine release during meditation associated with the experience of reduced readiness for action. It is suggested that being in the conscious state of meditation causes a suppression of cortico-striat al glutamatergic transmission.
- Time moves too slowly for hyperactive boys - health - 10 June 2009 - New Scientist: CHILDREN with attention-defi cit hyperactivity disorder might appear rowdy and indisciplined, but they are actually trying to cope with a faulty perception of time. What to most of us seems like a short stretch of time would drag unbearably for someone with ADHD, says Katya Rubia of the Institute of Psychiatry at King's College London. Her team's research, reported this week, adds to a growing body of evidence for the importance of time perception in a wide range of psychological disorders.
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New findings on Parkinson's disease and effect on patient behavior - PhysOrg
A new neuropsychological memory test is helping to uncover how Parkinson's disease can alter people's ability to learn about the consequences of the choices they make. The test was developed by Dr. Mark Gluck, professor of neuroscience at the Center ...
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