RelatedLinks

December 10th

December 5th

December 4th

  • Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission -- Rouach et al. 322 (5907): 1551 -- Science: The gap-junction subunit proteins connexin 43 and 30 allow intercellular trafficking of glucose and its metabolites through astroglial networks. This trafficking is regulated by glutamatergic synaptic activity mediated by AMPA receptors. In the absence of extracellular glucose, the delivery of glucose or lactate to astrocytes sustains glutamatergic synaptic transmission and epileptiform activity only when they are connected by gap junctions. These results indicate that astroglial gap junctions provide an activity-depen dent intercellular pathway for the delivery of energetic metabolites from blood vessels to distal neurons.

November 7th

November 5th

  • Deric Bownds' MindBlog: Does absolute brain size matter?: "A review by Marino of an article by Sherwood et al. in PNAS suggests that in ignoring absolute brain size we may have thrown out the baby with the bath water. [...] They indeed find that the human frontal cortex displays a higher ratio of glia to neurons than in other primates. However, and importantly, this relative difference is predicted by the allometric scaling inherent in the enlargement of the human brain. In other words, overall or absolute brain size constitutes a key factor in the ratio of glia to neurons. The authors suggest that the greater numbers of glia in the human neocortex may be due to the increased energetic costs of larger dendritic arbors and longer fiber projections within the context of the large human brain. The bottom line is that the human brain conforms to the general mammalian pattern of higher glia?neuron ratios with larger brains."

October 31st

October 22nd

October 16th

  • Effect of subchronic treatment of memantine, galan...[J Pharmacol Exp Ther. 2006] - PubMed Result: In Tg2576 mice (mutant APP expressing, APPswe).. nicotine compared to saline reduced guanidinum-sol uable amyloid-beta levels by 46-66%, left intracellular amyloid-beta levels unchanged, reduced glial fibrillary acidic protein immunoreactive astrocytes around the plaques, increased synaptophysin, and increased alpha7 nicotinic acetylcholine receptors in the cortex. Galantamine increased cortical levels of synapsophysin. Memantine reduced the total cortical levels of membrane-bound amyloid precursor protein (45-55%) in transgenic and non-transgenic mice.

September 24th

September 12th

August 26th

July 29th

    Video Buzz > Glia

    Format: AVI | MPEG | Real | Quicktime | Window Media

    No Matching Video

    No video for Glia is available at this time.

    Related Glia News

    Glia Podcasts

    Do you prefer to listen to your glia gossip? Check out Podzy Podcast Directory > Glia.

    Glia Products

    Looking for glia related products, then look no further. Try our new Glia Shop.


    Powered by Odin Assemble