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December 16th

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November 24th

November 19th

  • The Metabolic Effects of Insulin and Glucagon: Information regarding the different metabolic effects of both insulin and glucagon on the human body; as influenced by food intake and blood glucose levels. These were outlined in the Metabolism (MB1002) module.
  • Endocrine Pancreas: This is a useful website going into detail about te endocrine pancreas, with a lot of detail about the synthesis and effects of insulin and glucagon

November 18th

November 17th

  • Insulin and Glucagon metabolism: This website explains the secretion of insulin and glucagon within the body. It discusses the actions of both hormones during starvation and the fed state. This is also what we have been learning in the Metabolism lecture on endocrine pancreas.
  • Insulin Regulation of Blood Sugar and Diabetes: This explains how blood glucose levels are regulated via the use of hormones (insulin and glucagon) secreted from the pancreas. If blood glucose levels are high, insulin is secreted (from beta-cells) and if blood glucose levels are low, glucagon is secreted (from alpha-cells).

November 8th

  • Diabetic Ketoacidosis: Information containing consequences of ketoacids build up which lead to ketoacidosis in diabetic patients. This article provides a good understanding to the case study on hypoglycaemia and metabolic acidosis in the metabolism workbook.

August 28th

  • Terminally Ill Rodents With Type 1 Diabetes Restored To Full Health With Single Dose Of Leptin: 'The fact that these animals don?t die and are restored to normal health despite a total lack of insulin is hard for many researchers and clinicians to believe,' said Dr. Roger Unger...senior author of the study. 'Many scientists, including us, thought it would be a waste of time to give leptin in the absence of insulin. We?ve been brainwashed into thinking that insulin is the only substance that can correct the consequences of insulin deficiency.� 39; The mechanism of leptin?s glucose-loweri ng action appears to involve the suppression of glucagon, a hormone produced by the pancreas that raises glucose levels. Normally, glucagon is released when the glucose, or sugar, level in the blood is low. In insulin deficiency, however, glucagon levels are inappropriatel y high and cause the liver to release excessive amounts of glucose into the bloodstream. This action is opposed by insulin, which tells the body?s cells to remove sugar from the bloodstream.

July 30th

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