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April 13th
- Ongoing Beta-Glucan Clinical Trials - Clinical Trials Results - National Cancer Institute
- Definition of beta-glucan - National Cancer Institute Drug Dictionary: beta-glucan A polysaccharide isolated from the cell walls of bacteria, plants, and fungi with immunostimulan t and antineoplastic activities. In a solubilized form, beta-glucan binds to a lectin site within complement receptor 3 (CR3) on leukocytes, priming the receptor to trigger cytotoxic degranulation of leukocytes when leukocyte CR3 binds to complement 3 (iC3b)-coated tumors. Thus, the attachment of beta-glucan to CR3 of circulating leukocytes simulates leukocytes to kill iC3b-coated tumor cells in the same way as they kill iC3b-coated yeast. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
- Beta Glucan and its use in the alternative treatment of cancer: Beta Glucan is primarily cultured extract of Baker's Yeast cell wall. It is used as an immunostimulan t. Beta glucans are sugar molecules (polysaccharid es). They are found bound together as a sugar/protein complex. Certain plants and microorganisms are naturally high in this polysaccharide compound. The richest concentrated source is baker's yeast cell walls. (Because there is basically no yeast left in the products and they have low protein levels, it is considered hypoallergenic .) It is present in lesser amounts in mushroom extracts and Lentinen, Barley, Oat, etc. Sodium alginate is also an excellent source, but the high sodium content is a major drawback in the processing for supplemental use. An expensive research extract called Zymosan? has been used for doing research for over 45 years. Much of the research has been in combining it with conventional approaches, such as chemotherapy, but it has been found to work well on its own.
- Potent immunostimulan ts from microalgae invention: Potent immunostimulan ts from microalgae USPTO Application #: 20070059317 Title: Potent immunostimulan ts from microalgae Abstract: Immunostimulat ory polysaccharide s can be preferentially extracted from food-grade microalgae using an aqueous ethanol extraction procedure. The resulting preparations exhibit extremely potent immunostimulat ory activity. The preferential extraction of these immunostimulat ory polysaccharide s is dependent on the concentration of ethanol used and the extraction temperature. The most efficient conditions are 50% ethanol concentration at temperatures between 60° and 70° C. The isolated polysaccharide preparations are potentially useful as a botanical or pharmaceutical preparation to improve immune function.
- Chlorella, Herb Monograph - Flora Health Herb Encyclopedia: Chlorella, Chlorella pyrenoidosa and other Chlorella spp. [Phylum: Cyanophyta], is a nutrient-dense unicellular fresh water green alga rich in proteins (60%), vitamins, and minerals that is used as a source of food and beneficial phytochemicals . Chlorella has been on the earth since the Precambrian period: over 2.5 billion years. The cells of Chlorella were first identified under a microscope in the 1890s but it wasn't until the 1950s that the Carnegie Institute concluded that chlorella could be grown commercially as a solution to help world hunger. In the 1960s, Japanese scientists turned their attention to chlorella as a promoter of good health. Research has shown that Chlorella has strong detoxification , immunostimulan t and wound healing properties and prevents damage to the body from toxic chemicals.
April 12th
- Sloan-Ketterin g - Lentinan: Clinical Summary The polysaccharide , lentinan, is derived from the mycelium of the shiitake mushr oom body. It is considered a biological response modifier. In other countries, parenteral lentinan is classified as an antineoplastic polysaccharide and is available for clinical use. Only oral formulations and extracts, which are considered dietary supplements, are available for use in the United States. Data on efficacy and safety are limited regarding oral administration of lentinan.
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