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  • Regulatory T cell - Wikipedia, the free encyclopedia: Regulatory T cells (sometimes known as suppressor T cells) are a specialized subpopulation of T cells that act to suppress activation of the immune system and thereby maintain immune system homeostasis and tolerance to self-antigens. The existence of a dedicated population of suppressive T cells was the subject of significant controversy among immunologists for many years. However, recent advances in the molecular characterizati on of this cell population have firmly established their existence and their critical role in the vertebrate immune system. Interest in regulatory T cells has been heightened by evidence from experimental mouse models demonstrating that the immunosuppress ive potential of these cells can be harnessed therapeuticall y to treat autoimmune diseases and facilitate transplantatio n tolerance or specifically eliminated to potentiate cancer immunotherapy.
  • Cytotoxic T cell - Wikipedia, the free encyclopedia: A cytotoxic T cell (also known as TC, CTL, T-Killer cell, cytolytic T cell, CD8 T-cells or killer T cell) belongs to a sub-group of T lymphocytes (a type of white blood cell) that are capable of inducing the death of infected somatic or tumor cells

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  • Specialized White Blood Cells Coordinate First Responders To Viral Infection: According to recent studies by University of Washington (UW) scientists, specialized types of white blood cells, a category called regulatory T cells, seem to help orchestrate this timely reaction to a virus invasion. The Rudensky laboratory is noted for many contributions to the superhot field of regulatory T cells. These cells are important in controlling autoimmunity, a cellular self-attack that can lead to diseases like reactive arthritis. UW researchers and other scientists have shown that young mice deficient in regulatory T cells die from an aggressive form of autoimmunity that damages several organs.

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  • Dendreon: Active Cellular Immunotherapy: With a very dramatic video presenting the mechanism of action of their prospective prostate cancer drug; it does explain the theory behind it very well, though.

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