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June 10th

February 8th

  • Clofarabine Induces Hypomethylatio n of DNA and Expression of Cancer-Testis Antigens -- Zhang et al. 112 (11): 379 -- ASH Annual Meeting Abstracts: Clofarabine is a second generation purine nucleoside analogue, active in non-dividing cells and in cells with a low proliferation rate. It has been used in patients with refractory AML, ALL and MDS. In vitro data suggests that clofarabine induces cytotoxicity through inhibition of DNA synthesis. Clofarabine also induces apoptosis and disrupts the integrity of mitochondria. Cancer-Testis (CT) antigens are a group of normal testicular proteins aberrantly expressed in tumor cells. They are potential targets for tumor vaccine development because of their limited expression in normal tissues and their in vivo immunogenicity .

January 28th

November 19th

  • Undescended Testicles in Infants Linked to Genetic Abnormalities: In a small percentage of the study population, there was a statistically significant association between bilateral and persistent cryptorchidism and genetic alterations, including Klinefelter syndrome and INSL3 receptor gene mutations. http://jama.am a-assn.org/cgi /content/short /300/19/2271

October 20th

September 7th

  • Testis Kanseri: Testis tümörleri, genellikle genç erkekleri etkileyen ve ender görülen kanser türleri aras?nda.

August 1st

  • Prostate health: Prostate Health: Man Body Parts You Should Pay Attention

June 27th

April 6th

April 2nd

March 5th

February 10th

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