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June 30th

  • The W cell pathway to cat primary visual cortex: The Journal of Comparative Neurology: By combining light and electron microscopy, the authors have reconstructed in 3-D single W axons and described quantitatively the synapses that they form. W axons originating from C laminae injections arborized in layers 1, 2/3, and 5. Axons that traversed layer 1 supplied a few descending collaterals to layer 2/3, but the most extensive innervation in layer 2/3 was provided by axons ascending from the white matter. Most W boutons formed a single synapse, dendritic spines being the most common target, with dendritic shafts forming the remaining targets. In L1, the area of the postsynaptic density of spine synapses (0.16 m2) was significantly larger than that of L2/3 and 5 . Synapses from X and Y axons in L4 were similar in size to synapses formed by W boutons in layer 1. In layer 1, the main targets of the W axons are likely the apical dendrites of pyramidal cells, so that both proximal and distal regions of pyramidal cell dendritic trees can be excited by the W pathway.
  • Influence of Subcortical Inhibition on Barrel Cortex Receptive Fields -- Hirata et al. 102 (1): 437 -- Journal of Neurophysiolog y

June 27th

  • Your Brain Boots Up Like a Computer
  • Could a Dose of Ether Contain the Secret to Consciousness? | Drugs & Addiction | DISCOVER Magazine: "Although the brain may become less active under anesthesia, it usually doesn?t shut down completely (if it did, we would die). In fact, when scientists played a tone into the ears of an anesthetized cat, its cortex still produced strong bursts of electricity. But its responses were different from those of a waking cat. In an anesthetized cat, the brain responds the same way to any sound, with a noisy crackle of neurons. In a waking cat, the response is complex: One brain region after another responds as the animal processes the sound, and different sounds produce different responses. It?s as if the waking brain produces a unique melody, whereas the anesthetized brain can produce only a blast of sound or no sound at all."

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